diff --git a/.github/workflows/python-ci.yml b/.github/workflows/python-ci.yml
new file mode 100644
index 0000000..3dcfe84
--- /dev/null
+++ b/.github/workflows/python-ci.yml
@@ -0,0 +1,33 @@
+name: Python CI
+
+on:
+  push:
+    branches: [main]
+  pull_request:
+  workflow_dispatch:
+
+permissions:
+  contents: read
+
+concurrency:
+  group: ${{ github.workflow }}-${{ github.ref }}
+  cancel-in-progress: ${{ startsWith(github.ref, 'refs/pull/') }}
+
+jobs:
+  test:
+    name: Build & Test
+    runs-on: ubuntu-latest
+    timeout-minutes: 30
+    steps:
+      - uses: actions/checkout@3d3c42e5aac5ba805825da76410c181273ba90b1 # v7.0.1
+      - uses: jdx/mise-action@3c2e0cf82a5b2e5249f0d3635a4d83d0ae861518 # v4.2.5
+        with:
+          install_args: rust
+      - uses: Swatinem/rust-cache@6323deb102c322ba6fcbdcafc7e3dddab59af2b6 # v2.9.2
+      - uses: actions/setup-python@5fda3b95a4ea91299a34e894583c3862153e4b97 # v7.0.0
+        with:
+          python-version: "3.14"
+      - run: pip install maturin pytest typst
+      - run: maturin build --out dist
+      - run: pip install dist/*.whl
+      - run: pytest bindings/python/tests
diff --git a/.github/workflows/python-release.yml b/.github/workflows/python-release.yml
new file mode 100644
index 0000000..8c98b26
--- /dev/null
+++ b/.github/workflows/python-release.yml
@@ -0,0 +1,134 @@
+name: Python Release
+
+on:
+  push:
+    tags:
+      - "v*"
+  workflow_dispatch:
+
+permissions:
+  contents: read
+
+jobs:
+  linux:
+    name: Wheels (linux-${{ matrix.platform.target }})
+    runs-on: ${{ matrix.platform.runner || 'ubuntu-latest' }}
+    timeout-minutes: 60
+    strategy:
+      fail-fast: false
+      matrix:
+        platform:
+          - target: x86_64
+          - target: aarch64
+            runner: ubuntu-24.04-arm
+          - target: armv7
+          - target: s390x
+          - target: ppc64le
+    steps:
+      - uses: actions/checkout@3d3c42e5aac5ba805825da76410c181273ba90b1 # v7.0.1
+      - uses: actions/setup-python@5fda3b95a4ea91299a34e894583c3862153e4b97 # v7.0.0
+        with:
+          python-version: "3.14"
+      - name: Build wheels
+        uses: PyO3/maturin-action@e83996d129638aa358a18fbd1dfb82f0b0fb5d3b # v1.51.0
+        with:
+          target: ${{ matrix.platform.target }}
+          args: --release --out dist
+          manylinux: auto
+      - uses: actions/upload-artifact@043fb46d1a93c77aae656e7c1c64a875d1fc6a0a # v7.0.1
+        with:
+          name: wheels-linux-${{ matrix.platform.target }}
+          path: dist
+          if-no-files-found: error
+
+  macos:
+    name: Wheels (macos-${{ matrix.target }})
+    runs-on: macos-latest
+    timeout-minutes: 60
+    strategy:
+      fail-fast: false
+      matrix:
+        target: [x86_64, aarch64]
+    steps:
+      - uses: actions/checkout@3d3c42e5aac5ba805825da76410c181273ba90b1 # v7.0.1
+      - uses: jdx/mise-action@3c2e0cf82a5b2e5249f0d3635a4d83d0ae861518 # v4.2.5
+        with:
+          install_args: rust
+      - uses: actions/setup-python@5fda3b95a4ea91299a34e894583c3862153e4b97 # v7.0.0
+        with:
+          python-version: "3.14"
+      - name: Build wheels
+        uses: PyO3/maturin-action@e83996d129638aa358a18fbd1dfb82f0b0fb5d3b # v1.51.0
+        with:
+          target: ${{ matrix.target }}
+          args: --release --out dist
+      - uses: actions/upload-artifact@043fb46d1a93c77aae656e7c1c64a875d1fc6a0a # v7.0.1
+        with:
+          name: wheels-macos-${{ matrix.target }}
+          path: dist
+          if-no-files-found: error
+
+  windows:
+    name: Wheels (windows-${{ matrix.target }})
+    runs-on: windows-latest
+    timeout-minutes: 60
+    strategy:
+      fail-fast: false
+      matrix:
+        target: [x64]
+    steps:
+      - uses: actions/checkout@3d3c42e5aac5ba805825da76410c181273ba90b1 # v7.0.1
+      - uses: jdx/mise-action@3c2e0cf82a5b2e5249f0d3635a4d83d0ae861518 # v4.2.5
+        with:
+          install_args: rust
+      - uses: actions/setup-python@5fda3b95a4ea91299a34e894583c3862153e4b97 # v7.0.0
+        with:
+          python-version: "3.14"
+          architecture: ${{ matrix.target }}
+      - name: Build wheels
+        uses: PyO3/maturin-action@e83996d129638aa358a18fbd1dfb82f0b0fb5d3b # v1.51.0
+        with:
+          target: ${{ matrix.target }}
+          args: --release --out dist
+      - uses: actions/upload-artifact@043fb46d1a93c77aae656e7c1c64a875d1fc6a0a # v7.0.1
+        with:
+          name: wheels-windows-${{ matrix.target }}
+          path: dist
+          if-no-files-found: error
+
+  sdist:
+    name: sdist
+    runs-on: ubuntu-latest
+    timeout-minutes: 30
+    steps:
+      - uses: actions/checkout@3d3c42e5aac5ba805825da76410c181273ba90b1 # v7.0.1
+      - name: Build sdist
+        uses: PyO3/maturin-action@e83996d129638aa358a18fbd1dfb82f0b0fb5d3b # v1.51.0
+        with:
+          command: sdist
+          args: --out dist
+      - uses: actions/upload-artifact@043fb46d1a93c77aae656e7c1c64a875d1fc6a0a # v7.0.1
+        with:
+          name: wheels-sdist
+          path: dist
+          if-no-files-found: error
+
+  release:
+    name: Publish to PyPI
+    if: startsWith(github.ref, 'refs/tags/v')
+    needs: [linux, macos, windows, sdist]
+    runs-on: ubuntu-latest
+    timeout-minutes: 10
+    permissions:
+      id-token: write
+    steps:
+      - uses: actions/download-artifact@3e5f45b2cfb9172054b4087a40e8e0b5a5461e7c # v8.0.1
+        with:
+          pattern: wheels-*
+          path: dist
+          merge-multiple: true
+      - name: Publish to PyPI
+        uses: pypa/gh-action-pypi-publish@dc37677b2e1c63e2034f94d8a5b11f265b73ba33 # v1.14.2
+        with:
+          packages-dir: dist
+          skip-existing: true
diff --git a/.gitignore b/.gitignore
index ad67955..1f3bedb 100644
--- a/.gitignore
+++ b/.gitignore
@@ -13,6 +13,15 @@ target
 # Contains mutation testing data
 **/mutants.out*/
 
+# Python bindings build artifacts
+__pycache__/
+*.egg-info/
+.pytest_cache/
+dist/
+.venv/
+*.so
+*.pyd
+
 # RustRover
 #  JetBrains specific template is maintained in a separate JetBrains.gitignore that can
 #  be found at https://github.com/github/gitignore/blob/main/Global/JetBrains.gitignore
diff --git a/Cargo.lock b/Cargo.lock
index 5d51feb..086926b 100644
--- a/Cargo.lock
+++ b/Cargo.lock
@@ -283,6 +283,63 @@ dependencies = [
  "unicode-ident",
 ]
 
+[[package]]
+name = "pyo3"
+version = "0.29.2"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "4688ddedf473e32662b9b067670129a8afb8c18e351482c70d62ba4a88171e8b"
+dependencies = [
+ "libc",
+ "once_cell",
+ "portable-atomic",
+ "pyo3-build-config",
+ "pyo3-ffi",
+ "pyo3-macros",
+]
+
+[[package]]
+name = "pyo3-build-config"
+version = "0.29.2"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "f41027e41b4bd03f6e60f9f417fe24a6341a6bb744edd62b6f709f2a52ea30e9"
+dependencies = [
+ "target-lexicon",
+]
+
+[[package]]
+name = "pyo3-ffi"
+version = "0.29.2"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "e591a95526fead067432c3b3a33fc74770b87b1e04e73671090d9c2055a2b327"
+dependencies = [
+ "libc",
+ "pyo3-build-config",
+]
+
+[[package]]
+name = "pyo3-macros"
+version = "0.29.2"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "73225868fc1cd84eef2c3c230ddb91273bf1de46aeb8a4248da76d32a0924a1c"
+dependencies = [
+ "proc-macro2",
+ "pyo3-macros-backend",
+ "quote",
+ "syn",
+]
+
+[[package]]
+name = "pyo3-macros-backend"
+version = "0.29.2"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "571575aa3749fa6216757dd47d2a3e7ef360f329a40f0666a9fbd14889024952"
+dependencies = [
+ "heck",
+ "proc-macro2",
+ "quote",
+ "syn",
+]
+
 [[package]]
 name = "quote"
 version = "1.0.44"
@@ -420,6 +477,12 @@ dependencies = [
  "unicode-ident",
 ]
 
+[[package]]
+name = "target-lexicon"
+version = "0.13.5"
+source = "registry+https://github.com/rust-lang/crates.io-index"
+checksum = "adb6935a6f5c20170eeceb1a3835a49e12e19d792f6dd344ccc76a985ca5a6ca"
+
 [[package]]
 name = "thin-vec"
 version = "0.2.16"
@@ -478,6 +541,14 @@ dependencies = [
  "typst-syntax",
 ]
 
+[[package]]
+name = "typdiff-python"
+version = "0.1.2"
+dependencies = [
+ "pyo3",
+ "typdiff",
+]
+
 [[package]]
 name = "typst-syntax"
 version = "0.14.2"
diff --git a/Cargo.toml b/Cargo.toml
index 4808d9e..70b1285 100644
--- a/Cargo.toml
+++ b/Cargo.toml
@@ -1,11 +1,19 @@
+[workspace]
+members = ["bindings/python"]
+
+[workspace.package]
+version = "0.1.2"
+edition = "2024"
+license = "Apache-2.0"
+
 [package]
 name = "typdiff"
-version = "0.1.2"
+version.workspace = true
 authors = ["@sou1118"]
-edition = "2024"
+edition.workspace = true
 description = "A diff tool for Typst documents, similar to latexdiff"
 repository = "https://github.com/sou1118/typdiff"
-license = "Apache-2.0"
+license.workspace = true
 readme = "README.md"
 
 [[bin]]
diff --git a/README.md b/README.md
index 2ae40bf..3932825 100644
--- a/README.md
+++ b/README.md
@@ -98,6 +98,38 @@ typdiff old.typ new.typ -o diff.typ
 typdiff old.typ new.typ -o diff.typ && typst compile diff.typ
 ```
 
+## Python
+
+`typdiff` is also available as a Python package.
+
+### Installation
+
+```sh
+pip install typdiff
+```
+
+### Usage
+
+```python
+import typdiff
+
+diff = typdiff.diff(old_bytes, new_bytes)  # from bytes
+diff = typdiff.diff_files("old.typ", "new.typ")  # from file paths (str or Path)
+```
+
+`diff()` takes and returns `bytes`, matching how [`typst`](https://pypi.org/project/typst/)'s `compile()` treats `bytes` as inline source (a plain `str` argument is instead treated as a path to read) — so `typdiff`'s output can be passed straight into `compile()`. `diff_files()` still takes file paths as `str`/`Path`, since those are paths rather than document content.
+
+### Producing a PDF
+
+Combine `typdiff` with `typst` (Python bindings for the Typst compiler, `pip install typst`) to go straight from two Typst files to a diff PDF, without shelling out to either CLI:
+
+```python
+import typdiff
+import typst
+
+pdf_bytes = typst.compile(typdiff.diff_files("old.typ", "new.typ"))
+```
+
 ## Features
 
 - **Block-level diffing** — Detects structural changes in headings, paragraphs, list items, enum items, and term list items
diff --git a/bindings/python/Cargo.toml b/bindings/python/Cargo.toml
new file mode 100644
index 0000000..e298d8e
--- /dev/null
+++ b/bindings/python/Cargo.toml
@@ -0,0 +1,14 @@
+[package]
+name = "typdiff-python"
+version.workspace = true
+edition.workspace = true
+license.workspace = true
+publish = false
+
+[lib]
+name = "_typdiff"
+crate-type = ["cdylib"]
+
+[dependencies]
+typdiff = { path = "../.." }
+pyo3 = { version = "0.29", features = ["extension-module", "abi3-py38"] }
diff --git a/bindings/python/python/typdiff/__init__.py b/bindings/python/python/typdiff/__init__.py
new file mode 100644
index 0000000..5b21244
--- /dev/null
+++ b/bindings/python/python/typdiff/__init__.py
@@ -0,0 +1,3 @@
+from ._typdiff import diff, diff_files
+
+__all__ = ["diff", "diff_files"]
diff --git a/bindings/python/python/typdiff/__init__.pyi b/bindings/python/python/typdiff/__init__.pyi
new file mode 100644
index 0000000..8a70353
--- /dev/null
+++ b/bindings/python/python/typdiff/__init__.pyi
@@ -0,0 +1,7 @@
+import os
+
+def diff(old: bytes, new: bytes) -> bytes:
+    """Diff two Typst documents given as source bytes, returning diff markup as bytes."""
+
+def diff_files(old_path: str | os.PathLike[str], new_path: str | os.PathLike[str]) -> bytes:
+    """Diff two Typst documents given as file paths, returning diff markup as bytes."""
diff --git a/bindings/python/python/typdiff/py.typed b/bindings/python/python/typdiff/py.typed
new file mode 100644
index 0000000..e69de29
diff --git a/bindings/python/src/lib.rs b/bindings/python/src/lib.rs
new file mode 100644
index 0000000..aa587c3
--- /dev/null
+++ b/bindings/python/src/lib.rs
@@ -0,0 +1,43 @@
+use std::path::PathBuf;
+
+use pyo3::exceptions::{PyOSError, PyValueError};
+use pyo3::prelude::*;
+
+fn diff_sources(old: &str, new: &str) -> Vec<u8> {
+    let filter = |b: &typdiff::Block| !matches!(b, typdiff::Block::Parbreak);
+    let old_blocks: Vec<_> = typdiff::parse::parse(old)
+        .into_iter()
+        .filter(filter)
+        .collect();
+    let new_blocks: Vec<_> = typdiff::parse::parse(new)
+        .into_iter()
+        .filter(filter)
+        .collect();
+    let diff_results = typdiff::diff::diff(&old_blocks, &new_blocks);
+    typdiff::render::render(&diff_results).into_bytes()
+}
+
+/// Diff two Typst documents given as source bytes, returning diff markup as
+/// bytes (matching what typst.compile() expects for inline source).
+#[pyfunction]
+fn diff(old: &[u8], new: &[u8]) -> PyResult<Vec<u8>> {
+    let old = std::str::from_utf8(old).map_err(|e| PyValueError::new_err(e.to_string()))?;
+    let new = std::str::from_utf8(new).map_err(|e| PyValueError::new_err(e.to_string()))?;
+    Ok(diff_sources(old, new))
+}
+
+/// Diff two Typst documents given as file paths, returning diff markup as
+/// bytes (matching what typst.compile() expects for inline source).
+#[pyfunction]
+fn diff_files(old_path: PathBuf, new_path: PathBuf) -> PyResult<Vec<u8>> {
+    let old = std::fs::read_to_string(&old_path).map_err(|e| PyOSError::new_err(e.to_string()))?;
+    let new = std::fs::read_to_string(&new_path).map_err(|e| PyOSError::new_err(e.to_string()))?;
+    Ok(diff_sources(&old, &new))
+}
+
+#[pymodule]
+fn _typdiff(m: &Bound<'_, PyModule>) -> PyResult<()> {
+    m.add_function(wrap_pyfunction!(diff, m)?)?;
+    m.add_function(wrap_pyfunction!(diff_files, m)?)?;
+    Ok(())
+}
diff --git a/bindings/python/tests/test_diff.py b/bindings/python/tests/test_diff.py
new file mode 100644
index 0000000..f7c867d
--- /dev/null
+++ b/bindings/python/tests/test_diff.py
@@ -0,0 +1,48 @@
+from pathlib import Path
+
+import pytest
+
+import typdiff
+
+FIXTURES = Path(__file__).parents[3] / "tests" / "fixtures"
+
+
+def test_diff():
+    old = (FIXTURES / "old.typ").read_bytes()
+    new = (FIXTURES / "new.typ").read_bytes()
+
+    output = typdiff.diff(old, new)
+
+    assert isinstance(output, bytes)
+    assert b"#diff-deleted[Introduction]" in output
+    assert b"#diff-added[Background]" in output
+    assert b"#diff-deleted[Second]#diff-added[Third] item" in output
+
+
+@pytest.mark.parametrize("as_path", [str, Path])
+def test_diff_files(as_path):
+    output = typdiff.diff_files(as_path(FIXTURES / "old.typ"), as_path(FIXTURES / "new.typ"))
+
+    assert output == typdiff.diff(
+        (FIXTURES / "old.typ").read_bytes(), (FIXTURES / "new.typ").read_bytes()
+    )
+
+
+def test_diff_files_missing():
+    with pytest.raises(OSError):
+        typdiff.diff_files(str(FIXTURES / "does-not-exist.typ"), str(FIXTURES / "new.typ"))
+
+
+def test_diff_invalid_utf8():
+    with pytest.raises(ValueError):
+        typdiff.diff(b"\xff\xfe", b"new")
+
+
+@pytest.mark.pdf
+def test_diff_compiles_to_pdf():
+    typst = pytest.importorskip("typst")
+
+    output = typdiff.diff_files(FIXTURES / "old.typ", FIXTURES / "new.typ")
+    pdf = typst.compile(output)
+
+    assert pdf.startswith(b"%PDF-")
diff --git a/pyproject.toml b/pyproject.toml
new file mode 100644
index 0000000..9f8eb18
--- /dev/null
+++ b/pyproject.toml
@@ -0,0 +1,41 @@
+[build-system]
+requires = ["maturin>=1.9,<2.0"]
+build-backend = "maturin"
+
+[project]
+name = "typdiff"
+requires-python = ">=3.8"
+classifiers = [
+    "Programming Language :: Rust",
+    "Programming Language :: Python :: Implementation :: CPython",
+]
+dynamic = ["version"]
+dependencies = []
+license = "Apache-2.0"
+license-files = ["LICENSE"]
+description = "A diff tool for Typst documents, similar to latexdiff for LaTeX."
+readme = "README.md"
+
+[project.urls]
+Homepage = "https://github.com/sou1118/typdiff"
+Repository = "https://github.com/sou1118/typdiff"
+Readme = "https://github.com/sou1118/typdiff/blob/main/README.md"
+
+[dependency-groups]
+dev = [
+    "pytest>=8",
+]
+pdf = [
+    "typst>=0.13",
+]
+
+[tool.pytest.ini_options]
+markers = [
+    "pdf: exercises compiling typdiff output to PDF via the `typst` package (optional, requires the `pdf` dependency group)",
+]
+
+[tool.maturin]
+manifest-path = "bindings/python/Cargo.toml"
+module-name = "typdiff._typdiff"
+python-source = "bindings/python/python"
+features = ["pyo3/extension-module"]