diff --git a/py/setup.cfg b/py/setup.cfg
index d079d08d..e3a63a29 100644
--- a/py/setup.cfg
+++ b/py/setup.cfg
@@ -20,10 +20,10 @@ classifiers =
 [options]
 packages = find:
 platforms = any
-python_requires = >=3.6
+python_requires = >=3.8
 setup_requires =
     setuptools_scm
 install_requires =
-    protobuf >= 3.6.1
-    grpcio >= 1.17.2
+    protobuf >= 4.21.6
+    grpcio >= 1.49.1
     googleapis-common-protos >= 1.52