diff --git a/packages/x/components/suggestion/__tests__/index.test.tsx b/packages/x/components/suggestion/__tests__/index.test.tsx
index fc182a450..2bbed68bd 100644
--- a/packages/x/components/suggestion/__tests__/index.test.tsx
+++ b/packages/x/components/suggestion/__tests__/index.test.tsx
@@ -2,6 +2,7 @@ import { fireEvent, render, screen } from '@testing-library/react';
 import React from 'react';
 import mountTest from '../../../tests/shared/mountTest';
 import rtlTest from '../../../tests/shared/rtlTest';
+import Sender, { type SenderProps } from '../../sender';
 import Suggestion, { type SuggestionProps } from '../index';
 
 describe('Suggestion Component', () => {
@@ -84,6 +85,42 @@ describe('Suggestion Component', () => {
     expect(onOpenChange).toHaveBeenCalledWith(false);
   });
 
+  it('should not prevent Space input whether the popup is closed or open', () => {
+    const items = [{ label: 'Suggestion 1', value: 'suggestion1' }];
+    const { container } = render(<MockSuggestion items={items} />);
+    const input = container.querySelector('input')!;
+
+    expect(fireEvent.keyDown(input, { key: ' ' })).toBe(true);
+
+    fireEvent.keyDown(input, { key: '/' });
+    expect(screen.getByText('Suggestion 1')).toBeInTheDocument();
+    expect(fireEvent.keyDown(input, { key: ' ' })).toBe(true);
+  });
+
+  it.each<[name: string, senderProps: SenderProps, targetSelector: string]>([
+    ['textarea', {}, 'textarea'],
+    [
+      'input slot',
+      { slotConfig: [{ type: 'input', key: 'input' }] },
+      'input[data-slot-input="input"]',
+    ],
+    [
+      'contenteditable slot',
+      { slotConfig: [{ type: 'content', key: 'content' }] },
+      '[data-slot-key="content"][contenteditable="true"]',
+    ],
+  ])('should preserve Space input in a Sender %s', (_, senderProps, targetSelector) => {
+    const items = [{ label: 'Suggestion 1', value: 'suggestion1' }];
+    const { container } = render(
+      <Suggestion items={items} open>
+        {({ onKeyDown }) => <Sender {...senderProps} onKeyDown={onKeyDown} />}
+      </Suggestion>,
+    );
+    const target = container.querySelector<HTMLElement>(targetSelector)!;
+
+    expect(fireEvent.keyDown(target, { key: ' ' })).toBe(true);
+  });
+
   it('open controlled', () => {
     const items = [
       { label: 'Suggestion 1', value: 'suggestion1', icon: <div className="bamboo" /> },
diff --git a/packages/x/components/suggestion/__tests__/useActive.test.tsx b/packages/x/components/suggestion/__tests__/useActive.test.tsx
index d32c48862..4e45b93ad 100644
--- a/packages/x/components/suggestion/__tests__/useActive.test.tsx
+++ b/packages/x/components/suggestion/__tests__/useActive.test.tsx
@@ -270,6 +270,70 @@ describe('useActive', () => {
       const [activePaths] = result.current;
       expect(activePaths).toEqual([]);
     });
+
+    const dispatchSpace = (
+      target: HTMLElement,
+      options: { open?: boolean; altKey?: boolean; ctrlKey?: boolean; metaKey?: boolean } = {},
+    ) => {
+      const items: SuggestionItem[] = [{ label: 'Item 1', value: 'item1' }];
+      const stopPropagation = jest.fn();
+      const preventDefault = jest.fn();
+      const { open = true, ...modifiers } = options;
+      const { result } = renderHook(() => useActive(items, open, false, jest.fn()));
+
+      act(() =>
+        result.current[1]({
+          key: ' ',
+          target,
+          stopPropagation,
+          preventDefault,
+          ...modifiers,
+        } as any),
+      );
+
+      return { preventDefault, stopPropagation };
+    };
+
+    it.each([true, false])(
+      'should stop plain Space propagation from an editable target when open is %s',
+      (open) => {
+        const { preventDefault, stopPropagation } = dispatchSpace(
+          document.createElement('textarea'),
+          { open },
+        );
+
+        expect(stopPropagation).toHaveBeenCalledTimes(1);
+        expect(preventDefault).not.toHaveBeenCalled();
+      },
+    );
+
+    it('should stop plain Space propagation from a contenteditable target', () => {
+      const target = document.createElement('div');
+      Object.defineProperty(target, 'isContentEditable', { value: true });
+
+      expect(dispatchSpace(target).stopPropagation).toHaveBeenCalledTimes(1);
+    });
+
+    it.each([
+      ['Alt', { altKey: true }],
+      ['Control', { ctrlKey: true }],
+      ['Meta', { metaKey: true }],
+    ])('should not stop %s+Space propagation', (_, modifiers) => {
+      expect(
+        dispatchSpace(document.createElement('textarea'), modifiers).stopPropagation,
+      ).not.toHaveBeenCalled();
+    });
+
+    it.each([
+      ['button', document.createElement('button')],
+      ['button input', Object.assign(document.createElement('input'), { type: 'button' })],
+      ['checkbox input', Object.assign(document.createElement('input'), { type: 'checkbox' })],
+      ['number input', Object.assign(document.createElement('input'), { type: 'number' })],
+      ['readonly input', Object.assign(document.createElement('input'), { readOnly: true })],
+      ['disabled textarea', Object.assign(document.createElement('textarea'), { disabled: true })],
+    ])('should not stop Space propagation from a %s', (_, target) => {
+      expect(dispatchSpace(target).stopPropagation).not.toHaveBeenCalled();
+    });
   });
 
   describe('RTL mode', () => {
diff --git a/packages/x/components/suggestion/useActive.ts b/packages/x/components/suggestion/useActive.ts
index 60d6c8ee2..69043f9f2 100644
--- a/packages/x/components/suggestion/useActive.ts
+++ b/packages/x/components/suggestion/useActive.ts
@@ -2,6 +2,24 @@ import { useEvent } from '@rc-component/util';
 import React from 'react';
 import type { SuggestionItem } from '.';
 
+const TEXT_INPUT_TYPES = new Set(['email', 'password', 'search', 'tel', 'text', 'url']);
+
+const isEditableTarget = (target: EventTarget | null) => {
+  if (!(target instanceof HTMLElement)) {
+    return false;
+  }
+
+  if (target instanceof HTMLInputElement) {
+    return TEXT_INPUT_TYPES.has(target.type) && !target.disabled && !target.readOnly;
+  }
+
+  if (target instanceof HTMLTextAreaElement) {
+    return !target.disabled && !target.readOnly;
+  }
+
+  return target.isContentEditable;
+};
+
 /**
  * Since Cascader not support ref active, we use `value` to mock the active item.
  */
@@ -58,6 +76,10 @@ export default function useActive(
   };
 
   const onKeyDown: React.KeyboardEventHandler = useEvent((e) => {
+    if (e.key === ' ' && !e.altKey && !e.ctrlKey && !e.metaKey && isEditableTarget(e.target)) {
+      e.stopPropagation();
+    }
+
     if (!open) {
       return;
     }